*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : VS2878300 CHEMICAL NAME : 9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol, (1-alpha,3-beta,5Z,7E,24R)- CAS REGISTRY NUMBER : 56142-94-0 LAST UPDATED : 199806 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C27-H44-O4 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * (24R)-24-Hydroxycalcitriol * (1-alpha,3-beta,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25 -tetrol * Ro 21-7729 * 1-alpha,24(R),25-Trihydroxyvitamin D3 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 812 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - respiratory stimulation Nutritional and Gross Metabolic - body temperature decrease REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 17,4615,1989 *** END OF RECORD ***