*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VS3150000
CHEMICAL NAME           : 16,17-Secoestra-1,3,5(10)-trien-17-oic acid,
                          3-hydroxy-
CAS REGISTRY NUMBER     : 482-49-5
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H24-O3
MOLECULAR WEIGHT        : 288.42
WISWESSER LINE NOTATION : L B666&TTJ EQ K2 LVQ L1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Acido doisynolico
   * Doisynolic acid
   *   1-Ethyl-1,2,3,4,4a,9,10,10a-octahydro-7-hydroxy-2-methyl-2-phenanthrenec
     arboxylic acid
   *   1-Ethyl-7-hydroxy-2-methyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2-c
     arboxylic acid
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 72 mg/kg/12W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Reproductive - Tumorigenic effects - other reproductive system tumors
   Gastrointestinal - tumors
REFERENCE :
   RSABAC Revista de la Sociedad Argentina de Biologia.  (Sociedad Argentina de
   Biologia, Instituto de Biologia y Medicina Experimental, Obligado 2490, 1428
   Buenos Aires, Argentina)  V.1-    1925-  Volume(issue)/page/year:
   25,215,1949
 
                            *** END OF RECORD ***