*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VT3162000
CHEMICAL NAME           : Semicarbazide, 1,1-bis(2-chloroethyl)-
CAS REGISTRY NUMBER     : 78280-37-2
BEILSTEIN REFERENCE NO. : 2248538
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C5-H11-Cl2-N3-O
MOLECULAR WEIGHT        : 200.09
WISWESSER LINE NOTATION : ZVMN2G2G
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,1-Bis(2-chloraethyl)semicarbazid
   * 1,1-Bis(2-chloroethyl)semicarbazide
   * 1-Carbamoyl-2,2-bis(2-chloroethyl)hydrazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 375 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 8,543,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 12,260,1962
 
                            *** END OF RECORD ***