*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VT9625300
CHEMICAL NAME           : L-Serine, 2-diazo-3-hydroxybutanoate (ester), (R)-
CAS REGISTRY NUMBER     : 120128-14-5
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H11-N3-O5
MOLECULAR WEIGHT        : 217.21
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * O-((3R)-2-Diazo-3-hydroxybutyryl)-L-serine
   * Thrazarine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1561,1988
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 10 mg/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1561,1988
 
                            *** END OF RECORD ***