*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : VV8925000
CHEMICAL NAME : Silicic acid, beryllium salt
CAS REGISTRY NUMBER : 15191-85-2
LAST UPDATED : 199712
DATA ITEMS CITED : 34
MOLECULAR FORMULA : O4-Si.2Be
MOLECULAR WEIGHT : 110.11
WISWESSER LINE NOTATION : BE2 SI-O4
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* Beryllium silicate (Be2SiO4)
* Beryllium silicic acid
* Beryllium orthosilicate
* Beryllium silicon oxide (Be2SiO4)
* Diberyllium monosilicate
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumor types after systemic administration not seen
spontaneously
REFERENCE :
AICCA6 Acta Unio Internationalis Contra Cancrum. (Louvain, Belgium) V.1-20,
1936-64. For publisher information, see IJCNAW. Volume(issue)/page/year:
7,171,1950
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Musculoskeletal - tumors
REFERENCE :
ARPAAQ Archives of Pathology. (Chicago, IL) V.5(3)-50(3), 1928-50;
V.70-99, 1960-75. For publisher information, see APLMAS.
Volume(issue)/page/year: 88,89,1969
*** REVIEWS ***
ACGIH TLV-SUSPECTED HUMAN CARCINOGEN
85INA8 "Documentation of the Threshold Limit Values and Biological Exposure
Indices," 5th ed., Cincinnati, OH, American Conference of Governmental
Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 6,1/BEI,1997
ACGIH TLV-TWA 0.002 mg(Be)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-Suspected human carcinogen
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 23,143,1980
IARC Cancer Review:Group 2A
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,127,1987
TOXICOLOGY REVIEW
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 9,105,1971
*** U.S. STANDARDS AND REGULATIONS ***
OSHA PEL (Gen Indu):8H TWA 0.002 mg(Be)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 0.002 mg(Be)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 0.002 mg(Be)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 0.002 mg(Be)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-ARAB Republic of Egypt:TWA 0.002 mg(Be)/m3 JAN 1993
OEL-AUSTRALIA:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-BELGIUM:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-DENMARK:TWA 0.001 mg(Be)/m3;Carcinogen JAN 1993
OEL-FINLAND:TWA 0.002 mg(Be)/m3;STEL 0.006 mg(Be)/m3;Carcinogen JAN 1993
OEL-FRANCE:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-GERMANY;Carcinogen JAN 1993
OEL-HUNGARY:STEL 0.001 mg(Be)/m3;Carcinogen JAN 1993
OEL-INDIA:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-JAPAN:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-THE NETHERLANDS:TWA 0.002 mg(Be)/m3 JAN 1993
OEL-THE PHILIPPINES:TWA 0.002 mg(Be)/m3 JAN 1993
OEL-POLAND:TWA 0.001 mg(Be)/m3 JAN 1993
OEL-RUSSIA:STEL 0.001 mg(Be)/m3;Carcinogen JAN 1993
OEL-SWEDEN:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-SWITZERLAND:TWA 0.002 mg(Be)/m3;Carcinogen JAN 1993
OEL-THAILAND:TWA 0.002 mg(Be)/m3;STEL 0.005 mg(Be)/m3 JAN 1993
OEL-TURKEY:TWA 0.002 mg(Be)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.002 mg(Be)/m3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO BERYLLIUM-air:CA not to exceed 0.0005 mg(Be)/m3
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
*** END OF RECORD ***