*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VW7800000
CHEMICAL NAME           : Simplexin, 12-(benzoyloxy)-22,23,24,25-tetradehydro-,
                          (12-beta,22E,24E)-
CAS REGISTRY NUMBER     : 60195-70-2
OTHER CAS REGISTRY NOS. : 61913-72-2
                          66673-22-1
LAST UPDATED            : 199009
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C37-H44-O10
MOLECULAR WEIGHT        : 648.81
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Gnidilatidin
   * Odoracin
   * Stillingia factor S(sub 6)
   * Yuanhuacin
   * Yuanhuacine
   * Yuanhuacium ester A
   * Yuanhuatie
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1700 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SCYYDZ Shengzhi Yu Biyun.  Reproduction and Contraception.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) 1980-
    Volume(issue)/page/year: 9(2),48,1989
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 6020 nmol/L
REFERENCE :
   EJCODS European Journal of Cancer and Clinical Oncology.  (Pergamon Press,
   c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591)  V.17(7)-
   25, 1981-89.  For publisher information, see EJCAEL Volume(issue)/page/year:
   22,45,1986
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 8400 nmol/L
REFERENCE :
   EJCODS European Journal of Cancer and Clinical Oncology.  (Pergamon Press,
   c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591)  V.17(7)-
   25, 1981-89.  For publisher information, see EJCAEL Volume(issue)/page/year:
   22,45,1986
 
                            *** END OF RECORD ***