*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : WD7175000
CHEMICAL NAME : Sodium, (N(sup 1)-2-pyridylsulfanilamido)-
CAS REGISTRY NUMBER : 127-57-1
LAST UPDATED : 199701
DATA ITEMS CITED : 12
MOLECULAR FORMULA : C11-H10-N3-O2-S.Na
MOLECULAR WEIGHT : 271.29
WISWESSER LINE NOTATION : T6NJ BMSWR DZ &-NA-
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Benzenesulfonamide, 4-amino-N-2-pyridinyl-, monosodium salt
* N(sup 1)-2-Pyridylsulfanilamide sodium salt
* Sodium sulfapymonohydrate
* Sodium sulfapyridine
* Sodium sulphapyridine
* Soluble sulfapyridine
* Soludagenan
* Sulfanilamide, N(sup 1)-2-pyridyl-, monosodium salt
* Sulfanilamide, N(sup 1)-2-pyridyl-, N(sup 1)-sodium deriv.
* Sulfapyridine sodium
* Sulfapyridine, sodium salt
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2994 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIDXA3 Journal of the Indiana State Medical Association. (Indiana State
Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908-
Volume(issue)/page/year: 33,503,1940
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 45,15,1940
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 648 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 33,80,1944
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 68,259,1940
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 910 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIDXA3 Journal of the Indiana State Medical Association. (Indiana State
Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908-
Volume(issue)/page/year: 33,503,1940
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 872 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 71,138,1941
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 696 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIDXA3 Journal of the Indiana State Medical Association. (Indiana State
Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908-
Volume(issue)/page/year: 33,503,1940
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1096 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIDXA3 Journal of the Indiana State Medical Association. (Indiana State
Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908-
Volume(issue)/page/year: 33,503,1940
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 43,328,1940
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : 600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIDXA3 Journal of the Indiana State Medical Association. (Indiana State
Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908-
Volume(issue)/page/year: 33,503,1940
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 693 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIDXA3 Journal of the Indiana State Medical Association. (Indiana State
Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908-
Volume(issue)/page/year: 33,503,1940
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***