*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WG7430000
CHEMICAL NAME           : Spectinomycin, sulfate, tetrahydrate
CAS REGISTRY NUMBER     : 64058-48-6
LAST UPDATED            : 199706
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C14-H24-N2-O7.O4-S.4H2-O
MOLECULAR WEIGHT        : 500.54
WISWESSER LINE NOTATION : T C666 BO DO GV IOTJ E1 HQ KM1 LQ MM1 NQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Actinospectacin, tetrahydrate, sulfate
   * Spectinomycin, tetrahydrate, sulfate
   * Trobicin sulfate
   * U-18409E
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
   Antibiotics, A Program of Upjohn Company Research Laboratory."  (Kalamazoo,
   MI 49001)  Volume(issue)/page/year: 2(6),-,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3867 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
   Antibiotics, A Program of Upjohn Company Research Laboratory."  (Kalamazoo,
   MI 49001)  Volume(issue)/page/year: 2(6),-,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1022 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
   Antibiotics, A Program of Upjohn Company Research Laboratory."  (Kalamazoo,
   MI 49001)  Volume(issue)/page/year: 2(6),-,1971

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X2808
       No. of Facilities: 403 (estimated)
       No. of Industries: 1
       No. of Occupations: 5
       No. of Employees: 4029 (estimated)
       No. of Female Employees: 2015 (estimated)

 
                            *** END OF RECORD ***