*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WG9805000
CHEMICAL NAME           : Spiro(benzofuran-2(3H),1'-(3)cyclohexene)-2',3-dione,
                          7-chloro-4,4',6-trimethoxy- 6'-beta-methyl-
CAS REGISTRY NUMBER     : 469-52-3
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H17-Cl-O6
MOLECULAR WEIGHT        : 352.79
WISWESSER LINE NOTATION : T56 BOXVJ FO1 HO1 IG C-& BL6VX EUTJ C1 EO1
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Isogriseofulvin
   * Isogriseofulvin-forte
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg
SEX/DURATION            : female 9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 18,655,1973
 
                            *** END OF RECORD ***