*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WH0194560
CHEMICAL NAME           : Spiro(cyclohexane-1,4'(1'H)-quinazoline)-2'(3'H)-thio
                          ne, 5',6',7',8'-tetrahydro-
CAS REGISTRY NUMBER     : 5579-43-1
LAST UPDATED            : 198408
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C13-H20-N2-S
MOLECULAR WEIGHT        : 236.41
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   5',6',7',8'-Tetrahydrospiro(cyclohexane-1,4'(1'H)-quinazoline)-2'(3'H)-t
     hione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1270 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   24,572,1969
 
                            *** END OF RECORD ***