*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WH1427000
CHEMICAL NAME           : Spiro(oxirane-2,1'(2H)-pentaleno(1,6a-c)pyran)-5'-car
                          boxylic acid, 4',4'a,6'a,7'-tetrahydro-
                          7',8'-dimethyl-2'-oxo-,
                          (1'R-(1'-alpha,4'a-alpha,6'a-beta,7'-alpha,9'aS*))-
CAS REGISTRY NUMBER     : 31501-48-1
LAST UPDATED            : 199506
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H16-O5
MOLECULAR WEIGHT        : 276.31
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic PA-132
   * Arenemycine
   * PA-132
   * Pentalenolactone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABANAE Antibiotics Annual.  (New York, NY)  1953-60.  For publisher
   information, see AMACCQ.  Volume(issue)/page/year: 4,676,1956/1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABANAE Antibiotics Annual.  (New York, NY)  1953-60.  For publisher
   information, see AMACCQ.  Volume(issue)/page/year: 4,676,1956/1957
 
                            *** END OF RECORD ***