*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : WJ5840000
CHEMICAL NAME : 4,4'-Stilbenediol,
alpha,alpha'-diethyl-3,3',5,5'-tetrafluoro-, (E)-
CAS REGISTRY NUMBER : 71292-84-7
LAST UPDATED : 199410
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C18-H16-F4-O2
MOLECULAR WEIGHT : 340.34
WISWESSER LINE NOTATION : QR BF FF DY2&UY2&R DQ CF EF
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* trans-alpha,alpha'-Diethyl-3,3',5,5'-tetrafluoro-4,4'-stilbenediol
* Phenol, 4,4'-(1,2-diethyl-1,2-ethenediyl)bis(2,6-difluoro-, (E)-
* E-3',5',3'',5''-Tetrafluorodiethylstilbestrol
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - hamster
DOSE/DURATION : 360 mg/kg/12W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
43,2678,1983
** MUTATION DATA **
TYPE OF TEST : Morphological transformation
TEST SYSTEM : Rodent - hamster Embryo
DOSE/DURATION : 10 ug/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
42,3040,1982
TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - hamster Embryo
DOSE/DURATION : 7 mg/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 7,1329,1986
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - hamster Embryo
DOSE/DURATION : 1 mg/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
44,184,1984
*** END OF RECORD ***