*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WK1969400
CHEMICAL NAME           : D-Streptamine,
                          O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(2-a
                          mino-2,3-dideoxy-alph a-
                          D-ribo-hexopyranosyl-(1-4))-2-deoxy-
CAS REGISTRY NUMBER     : 65566-75-8
LAST UPDATED            : 198609
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H36-N4-O10
MOLECULAR WEIGHT        : 468.58
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic 535
   * 3'-Deoxykanamycin C
   * 3'-Desoxykanamycin C
   * Kanamycin C, 3'-deoxy-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMBIEH Antibiotiki i Meditsinskaya Biotekhnologiya.  Antibiotics and Medical
   Biotechnology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.30-V.32,
   1985-1987  Volume(issue)/page/year: 30,743,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMBIEH Antibiotiki i Meditsinskaya Biotekhnologiya.  Antibiotics and Medical
   Biotechnology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.30-V.32,
   1985-1987  Volume(issue)/page/year: 30,743,1985
 
                            *** END OF RECORD ***