*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WK1970000
CHEMICAL NAME           : D-Streptamine,
                          O-4-amino-4-deoxy-alpha-D-glucopyranosyl-(1-8)-O-(8R)
                          -2-amino-2,3,7-trideo xy-
                          7-(methylamino)-D-glycero-alpha-D-allo-octadialdo-1,5
                          :8,4-dipyranosyl-(1-4 )-2-deoxy-
CAS REGISTRY NUMBER     : 37321-09-8
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H41-N5-O11
MOLECULAR WEIGHT        : 539.67
WISWESSER LINE NOTATION : T66 BO GOTJ DM1 EQ IZ CO- BT6OTJ CQ DQ EZ F1Q& HO-
                          BL6TJ AZ CQ DQ EZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ambylan
   * Apralan
   * Apramycin
   * EL 857
   * EL-857/820
   * Nebramycin factor 2
   * Nebramycin II
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 280 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38KLAC "Structure-Activity Relationship among the Semisynthetic
   Antibiotics,"  Perlman, D., ed., New York, Academic Press, 1977
   Volume(issue)/page/year: -,239,1977
 
                            *** END OF RECORD ***