*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WK2284000
CHEMICAL NAME           : D-Streptamine,
                          O-3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopy
                          ranosyl-
                          (1-6)-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-thre
                          o-hept-4-enopyranosyl -(1-4))-2-deoxy-
CAS REGISTRY NUMBER     : 49863-48-1
LAST UPDATED            : 198106
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C20-H39-N5-O7
MOLECULAR WEIGHT        : 461.64
WISWESSER LINE NOTATION : T6O BUTJ BYZ1 EZ FO- BL6TJ AZ CQ EZ DO- BT6OTJ CQ DM1
                          EQ E1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * 6'-C-Methylsisomicin
   * Verdamycin
   * Verdamycin 1
   * Verdamycin I
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMACCQ Antimicrobial Agents and Chemotherapy.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.1-    1972-
   Volume(issue)/page/year: 7,246,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMACCQ Antimicrobial Agents and Chemotherapy.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.1-    1972-
   Volume(issue)/page/year: 7,246,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 48 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMACCQ Antimicrobial Agents and Chemotherapy.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.1-    1972-
   Volume(issue)/page/year: 7,246,1975
 
                            *** END OF RECORD ***