*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WK2302000
CHEMICAL NAME           : D-Streptamine,
                          O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4
                          )-O-(beta-D- xylofuranosyl-(1-5))-N(sup
                          1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-
CAS REGISTRY NUMBER     : 34291-02-6
LAST UPDATED            : 198211
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H41-N5-O12
MOLECULAR WEIGHT        : 555.67
WISWESSER LINE NOTATION : T6OTJ B1Z CQ DQ EZ FO- BL6TJ AZ DQ EMVYQ2Z CO- BT5OTJ
                          CQ DQ E1Q
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ambutyrosin A
   * Ambuyrosin A
   * Butirosin A
   * Butyrosin A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2198 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 1,145,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3050 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 1,145,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 580 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38KLAC "Structure-Activity Relationship among the Semisynthetic
   Antibiotics,"  Perlman, D., ed., New York, Academic Press, 1977
   Volume(issue)/page/year: -,239,1977
 
                            *** END OF RECORD ***