*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WK4250000
CHEMICAL NAME           : Streptolydigin
CAS REGISTRY NUMBER     : 7229-50-7
LAST UPDATED            : 199403
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C32-H44-N2-O9
MOLECULAR WEIGHT        : 600.78
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Antibiotic D-45
   * Portamycin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 533 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
   Antibiotics, A Program of Upjohn Company Research Laboratory."  (Kalamazoo,
   MI 49001)  Volume(issue)/page/year: 2(6),-,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBPCBB Comparative Biochemistry and Physiology, C: Comparative Pharmacology.
    (Elsevier Science, POB 800, Kidlington, Oxford OX5 1DX, UK) V.50-73,
   1975-82.  For publisher information, see CBPCEE. Volume(issue)/page/year:
   66,83,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 288 mg/L
REFERENCE :
   FOMIAZ Folia Microbiologica (Prague).  (Academia, Vodickova 40, 112 29
   Prague 1, Czechoslavakia) V.4-    1959-  Volume(issue)/page/year:
   22,329,1977
 
                            *** END OF RECORD ***