*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WN2625000
CHEMICAL NAME           : Succinimide, N,2-dimethyl-2-phenyl-
CAS REGISTRY NUMBER     : 77-41-8
BEILSTEIN REFERENCE NO. : 0168315
REFERENCE               : 5-21-11-00209 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C12-H13-N-O2
MOLECULAR WEIGHT        : 203.26
WISWESSER LINE NOTATION : T5VNVTJ B1 D1 DR
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Celontin
   * 1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine
   * 1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dione
   * N,2-Dimethyl-2-phenylsuccinimide
   * Mesuximide
   * Methsuximide
   * N-Methyl-alpha-methyl-alpha-phenylsuccinimide
   * N-Methyl-alpha,alpha-methylphenylsuccinimide
   * alpha-Methylphensuximide
   * alpha-Methyl-alpha-phenyl N-methyl succinimide
   * Metsuccimide
   * Petinutin
   * PM 396
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 6,740,1954
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1006 mg/kg
SEX/DURATION            : female 8-10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 38,438,1979

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X6158
       No. of Facilities: 29 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 876 (estimated)
       No. of Female Employees: 408 (estimated)

 
                            *** END OF RECORD ***