*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WN3500000
CHEMICAL NAME           : Succinimide, thio-
CAS REGISTRY NUMBER     : 4166-00-1
BEILSTEIN REFERENCE NO. : 1524377
REFERENCE               : 5-21-09-00550 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C4-H5-N-O-S
MOLECULAR WEIGHT        : 115.16
WISWESSER LINE NOTATION : T5VMYTJ CUS
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Monothiosuccinimide
   * 2-Pyrrolidinone, 5-thioxo-
   * Thiosuccinimide
   * 2-Thiosuccinimide
   * USAF WI-1
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD414-344
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 29 gm/kg/2W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   68,397,1977
 
                            *** END OF RECORD ***