*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : WO9410000 CHEMICAL NAME : Sulfanilamide, N(sup 1)-(6-ethoxy-3-pyridazinyl)- CAS REGISTRY NUMBER : 963-14-4 BEILSTEIN REFERENCE NO. : 0286161 REFERENCE : 5-25-12-00430 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C12-H14-N4-O3-S MOLECULAR WEIGHT : 294.36 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Benzenesulfonamide, 4-amino-N-(6-ethoxy-3-pyridazinyl)- * Cysul * N(sup 1)-(6-Ethoxy-3-pyridazinyl)sulfanilamide * Sulfaethoxypyridazine *** HEALTH HAZARD DATA *** ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 16240 mg/kg/29W-I TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - changes in pituitary weight Endocrine - changes in thyroid weight REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 10,557,1967 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 30450 mg/kg/29W-I TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - changes in thyroid weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 10,557,1967 *** END OF RECORD ***