*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WO9500000
CHEMICAL NAME           : Sulfanilamide, N(sup
                          1)-(5-ethyl-1,3,4-thiadiazol-2-yl)-, monosodium salt
CAS REGISTRY NUMBER     : 63979-86-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H12-N4-O2-S2.Na
MOLECULAR WEIGHT        : 307.37
WISWESSER LINE NOTATION : T5NN DSJ CMSWR DZ& E2 &-NA-
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Benzenesulfonamide, 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-,  
   monosodium salt
   * Sodium sulfaethylthiadiazole
   * Sulfaethylthiadiazole sodium
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1243 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMSSAQ Acta Medica Scandinavica, Supplement.  (Almqvist & Wiksell, POB
   45150, S-10430 Stockholm, Sweden)  No.1-730, 1921-88.
   Volume(issue)/page/year: 142,64,1943
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1200 mg/kg
SEX/DURATION            : female 10-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - other neonatal measures or effects
REFERENCE :
   JHMJAX Johns Hopkins Medical Journal.  (Baltimore, MD)  V.120-151, 1967-82.
   Discontinued.  Volume(issue)/page/year: 130,95,1972
 
                            *** END OF RECORD ***