*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : WP0525000
CHEMICAL NAME : Sulfanilamide, N(sup 1)-(5-methoxy-2-pyrimidinyl)-
CAS REGISTRY NUMBER : 651-06-9
BEILSTEIN REFERENCE NO. : 0621130
REFERENCE : 5-25-12-00525 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 11
MOLECULAR FORMULA : C11-H12-N4-O3-S
MOLECULAR WEIGHT : 280.33
WISWESSER LINE NOTATION : T6N CNJ BMSWR DZ& EO1
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* AHR-857
* 2-(4-Aminobenzenesulfonamido)-5-methoxypyrimidine
* 4-Amino-N-(5-methoxy-2-pyrimidinyl)benzenesulfonamide
* Bayer 5400
* Bayrena
* Benzenesulfonamide, 4-amino-N-(5-methoxy-2-pyridimidinyl)-
* Berlicid
* Dairena
* Durenat
* Durisan
* I-2586
* Juvoxin
* Kinecid
* Kirocid
* Kiron
* Longasulf
* Methoxypyrimal
* 5-Methoxy-2-sulfanilamidopyrimidine
* N(sup 1)-(5-Methoxy-2-pyrimidinyl)sulfanilamide
* SH 613
* Sulfameter
* Sulfamethorine
* Sulfamethoxine
* Sulfamethoxydiazine
* Sulfamethoxydin
* Sulfamethoxypyrimidine
* Sulfa-5-methoxypyrimidine
* Sulfametin
* Sulfametorine
* Sulfametoxipirimidine
* 2-Sulfanilamido-5-methoxypyrimidin
* 2-Sulfanilamido-5-methoxypyrimidine
* Sulla
* Sulphameter
* Sulphamethoxydiazine
* Sulfa-5-methyldiazine
* Supramid
* Ultrax
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 6 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 11,695,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 11,695,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
12ZWAM "Experimental Chemotherapy, Volume II," Schnitzer, R.J., and F.
Hawking, eds. Academic Press, New York, 1964 Volume(issue)/page/year:
2,249,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
16,1367,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 11,695,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 11,695,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
12ZWAM "Experimental Chemotherapy, Volume II," Schnitzer, R.J., and F.
Hawking, eds. Academic Press, New York, 1964 Volume(issue)/page/year:
2,249,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 11,695,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 11,695,1961
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
12ZWAM "Experimental Chemotherapy, Volume II," Schnitzer, R.J., and F.
Hawking, eds. Academic Press, New York, 1964 Volume(issue)/page/year:
2,249,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 11,695,1961
*** END OF RECORD ***