*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WP0755000
CHEMICAL NAME           : Sulfanilamide, N(sup 1)-(5-methyl-2-pyrimidinyl)-
CAS REGISTRY NUMBER     : 599-88-2
BEILSTEIN REFERENCE NO. : 0249118
REFERENCE               : 5-25-10-00192 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H12-N4-O2-S
MOLECULAR WEIGHT        : 264.33
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-(p-Aminobenzenesulfonamido)-5-methylpyrimidine
   * 4-Amino-N-(5-methyl-2-pyrimidinyl)benzenesulfonamide
   * Anastaf
   * Archisulfa
   * Avissul
   * Benzenesulfonamide, 4-amino-N-(5-methyl-2-pyrimidinyl)-
   * BT 325
   * Chemiopen
   * Demosulfan
   * Isosulfamerazine
   * 5-Methylsulfadiazine
   * Orosulfan
   * Pallidin
   * Pallidin (pharmaceutical)
   * Panafil
   * Risulfasens
   * 2-(Sulfanilamido)-5-methylpyrimidine
   * Sulfaperin
   * Sulfaperine
   * Sulfatreis
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 10,440,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 10,440,1960
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 35 gm/kg/7W-I
TOXIC EFFECTS :
   Endocrine - evidence of thyroid hyperfunction
   Related to Chronic Data - death
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 10,440,1960
 
                            *** END OF RECORD ***