*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : WP0755000 CHEMICAL NAME : Sulfanilamide, N(sup 1)-(5-methyl-2-pyrimidinyl)- CAS REGISTRY NUMBER : 599-88-2 BEILSTEIN REFERENCE NO. : 0249118 REFERENCE : 5-25-10-00192 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C11-H12-N4-O2-S MOLECULAR WEIGHT : 264.33 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-(p-Aminobenzenesulfonamido)-5-methylpyrimidine * 4-Amino-N-(5-methyl-2-pyrimidinyl)benzenesulfonamide * Anastaf * Archisulfa * Avissul * Benzenesulfonamide, 4-amino-N-(5-methyl-2-pyrimidinyl)- * BT 325 * Chemiopen * Demosulfan * Isosulfamerazine * 5-Methylsulfadiazine * Orosulfan * Pallidin * Pallidin (pharmaceutical) * Panafil * Risulfasens * 2-(Sulfanilamido)-5-methylpyrimidine * Sulfaperin * Sulfaperine * Sulfatreis *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 16 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,440,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >8 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,440,1960 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 35 gm/kg/7W-I TOXIC EFFECTS : Endocrine - evidence of thyroid hyperfunction Related to Chronic Data - death REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,440,1960 *** END OF RECORD ***