*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WR6475000
CHEMICAL NAME           : Sulfone, ethyl p-fluorophenyl
CAS REGISTRY NUMBER     : 2924-67-6
BEILSTEIN REFERENCE NO. : 2364075
REFERENCE               : 4-06-00-01567 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C8-H9-F-O2-S
MOLECULAR WEIGHT        : 188.23
WISWESSER LINE NOTATION : WS2&R DF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bripadon
   * Caducid
   * Ethyl-p-fluorfenylsulfon
   * Ethyl p-fluorophenyl sulfone
   * 1-(Ethylsulfonyl)-4-fluorobenzene
   * Fluoresone
   * p-Fluorophenyl ethyl sulfone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 542 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEPSBV Neuropsychopharmacology, Proceedings of the Meeting of the Collogium
   Internationale, Neuropsychopharmacologicum.  (Excerpta Medica Foundation,
   P.O. Box 1126, Amsterdam, Netherlands)  V.1-    1959-
   Volume(issue)/page/year: 3,326,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 343 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEPSBV Neuropsychopharmacology, Proceedings of the Meeting of the Collogium
   Internationale, Neuropsychopharmacologicum.  (Excerpta Medica Foundation,
   P.O. Box 1126, Amsterdam, Netherlands)  V.1-    1959-
   Volume(issue)/page/year: 3,326,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEPSBV Neuropsychopharmacology, Proceedings of the Meeting of the Collogium
   Internationale, Neuropsychopharmacologicum.  (Excerpta Medica Foundation,
   P.O. Box 1126, Amsterdam, Netherlands)  V.1-    1959-
   Volume(issue)/page/year: 3,317,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEPSBV Neuropsychopharmacology, Proceedings of the Meeting of the Collogium
   Internationale, Neuropsychopharmacologicum.  (Excerpta Medica Foundation,
   P.O. Box 1126, Amsterdam, Netherlands)  V.1-    1959-
   Volume(issue)/page/year: 3,317,1962
 
                            *** END OF RECORD ***