*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WM2700000
CHEMICAL NAME           : Substance P
CAS REGISTRY NUMBER     : 516-47-2
LAST UPDATED            : 199709
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H34-O4
MOLECULAR WEIGHT        : 350.55
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Compound P
   * Pregnan-20-one, 3,17,21-trihydroxy-, (3-beta,5-alpha)-
   * 5-alpha-Pregnan-20-one, 3-beta,17,21-trihydroxy-
   * Reichstein's Substance P
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intrauterine
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 ug/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year: 30,80,1992
 
                            *** END OF RECORD ***