*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WU7679500
CHEMICAL NAME           : Sydnone imine,
                          3-(beta-hydroxy-alpha-methylphenethyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 17583-77-6
LAST UPDATED            : 199103
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H13-N3-O2.Cl-H
MOLECULAR WEIGHT        : 255.73
WISWESSER LINE NOTATION : T5NNOYJ AY1&YQR& DUM &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(beta-Hydroxy-alpha-methylphenethyl)sydnone imine monohydrochloride
   * 3-(1-Hydroxy-1-phenyl-2-propyl) sydnone imine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Skin and Appendages - hair
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 2,235,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 14,1013,1971
 
                            *** END OF RECORD ***