*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WU7694500
CHEMICAL NAME           : Sydrone, 3-p-tolyl-
CAS REGISTRY NUMBER     : 3483-19-0
BEILSTEIN REFERENCE NO. : 3672154
REFERENCE               : 4-27-00-07443 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C9-H8-N2-O2
MOLECULAR WEIGHT        : 176.19
WISWESSER LINE NOTATION : T5NNOVJ AR D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(4-Methylphenyl)sydnone
   * 1,2,3-Oxadiazolium, 5-hydroxy-3-(4-methylphenyl)-, inner salt
   * Sydnone, 3-(4-methylphenyl)-
   * N-(p-Tolyl)-sydnon
   * 3-(p-Tolyl)sydnone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 753 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Behavioral - anticonvulsant
   Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   14,369,1965
 
                            *** END OF RECORD ***