*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : WW2710000
CHEMICAL NAME : Talc (powder), containing no asbestos fibers
CAS REGISTRY NUMBER : 14807-96-6
LAST UPDATED : 199712
DATA ITEMS CITED : 31
MOLECULAR FORMULA : H2-03-Si.3/4Mg
MOLECULAR WEIGHT : 96.33
WISWESSER LINE NOTATION : .MG4.SI-O3*3
COMPOUND DESCRIPTOR : Tumorigen
Natural Product
Primary Irritant
SYNONYMS/TRADE NAMES :
* Agalite
* Asbestine
* B 9
* B 13
* Beaver White 200
* B 13 (mineral)
* CP 10-40
* CP 38-33
* Crystalite CRS 6002
* Desertalc 57
* Emtal 500
* Emtal 549
* Emtal 596
* Emtal 599
* EX-IT
* Fibrene C 400
* Finntalc C10
* Finntalc M05
* Finntalc M15
* Finntalc P40
* Finntalc PF
* FW-XO
* IT Extra
* LMR 100
* Micro Ace K1
* Micro Ace L1
* Micron White 5000A
* Micron White 5000P
* Micron White 5000S
* Microtalco IT Extra
* Mistron 139
* Mistron frost P
* Mistron RCS
* Mistron 2SC
* Mistron Star
* Mistron super frost
* Mistron vapor
* MP 12-50
* MP 25-38
* MP 40-27
* MP 45-26
* MST
* Mussolinite
* Nytal 200
* Nytal 400
* P 3
* PK-C
* PK-N
* P 3 (Mineral)
* Polytal 4641
* Polytal 4725
* Silicate: talc, containing no asbestos
* Steawhite
* Supreme
* Supreme dense
* Talc
* Talcan PK-P
* Talcron CP 44-31
* Talcum
* TY 80
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 300 ug/3D (Intermittent)
REACTION SEVERITY : Mild
REFERENCE :
85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill,
V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977
Volume(issue)/page/year: -,127,1977
** TUMORIGENIC DATA **
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 18 mg/m3/6H/2Y-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - bronchiogenic carcinoma
Endocrine - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-421,1993
TYPE OF TEST : TC - Toxic concentration (other than lowest)
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 11 mg/m3/1Y-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
REFERENCE :
43GRAK "Dusts and Disease, Proceedings of the Conference on Occupational
Exposures to Fibrous and Particulate Dust and Their Extension into the
Environment, 1977," Lemen, R., and J.M. Dement, eds., Park Forest South, IL,
Pathotox Pub., 1979 Volume(issue)/page/year: -,389,1979
*** REVIEWS ***
ACGIH TLV-Not classifiable as a human carcinogen
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-TWA 2 mg/m3, total dust
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 42,185,1987
IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 42,185,1987
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,349,1987
*** U.S. STANDARDS AND REGULATIONS ***
OSHA PEL (Gen Indu):8H TWA 20 mppcf, respirable dust
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 20 mppcf, respirable dust
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 20 mppcf
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 20 mppcf, respirable dust
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 2.5 mg/m3 JAN 1993
OEL-BELGIUM:TWA 2 mg/m3 JAN 1993
OEL-FINLAND:TWA 5 mg/m3 JAN 1993
OEL-GERMANY:TWA 2 mg/m3 JAN 1993
OEL-SWITZERLAND:TWA 10 mg/m3 (total dust) JAN 1993
OEL-SWITZERLAND:TWA 2 mg/m3 (resp. dust) JAN 1993
OEL-UNITED KINGDOM:TWA 1 mg/m3 (resp. dust) JAN 1993
OEL-UNITED KINGDOM:TWA 10 mg/m3 (total dust) JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO TALC (containing no asbestos)-air:10H 2 mg/m3
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: PHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 71055
No. of Facilities: 38349 (estimated)
No. of Industries: 243
No. of Occupations: 149
No. of Employees: 527353 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X9093
No. of Facilities: 273 (estimated)
No. of Industries: 2
No. of Occupations: 2
No. of Employees: 4245 (estimated)
No. of Female Employees: 590 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 71055
No. of Facilities: 82650 (estimated)
No. of Industries: 313
No. of Occupations: 192
No. of Employees: 1367384 (estimated)
No. of Female Employees: 348973 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NTP Carcinogenesis Studies (inhalation);clear evidence:rat
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-421,93
NTP Carcinogenesis Studies (inhalation);no evidence:mouse
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-421,93
*** END OF RECORD ***