*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : WX0400000
CHEMICAL NAME           : Taurine, N-choloyl-, sodium salt
CAS REGISTRY NUMBER     : 145-42-6
LAST UPDATED            : 199701
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C26-H44-N-O7-S.Na
MOLECULAR WEIGHT        : 537.76
WISWESSER LINE NOTATION : L E5 B666TJ A1 DQ E1 FY1&2VM2SWO KQ OQ &-NA- &42/32
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Monosodium taurocholic acid
   * Sodium taurocholate
   * Taurocholate sodium
   * Taurocholate sodium salt
   * Taurocholic acid sodium salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ZGEMAZ Zeitschrift fuer die Gesamte Experimentelle Medizin.  (Berlin, Fed.
   Rep. Ger.)  V.1-139, 1913-65.  For publisher information, see REXMAS.
   Volume(issue)/page/year: 52,779,1926
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Unscheduled DNA synthesis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1 gm/kg
REFERENCE :
   JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB
   211, 1000 AE Amsterdam, Netherlands)  V.76-    1985-
   Volume(issue)/page/year: 78,32,1987

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80529
       No. of Facilities: 126 (estimated)
       No. of Industries: 3
       No. of Occupations: 7
       No. of Employees: 3026 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80529
       No. of Facilities: 52 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 741 (estimated)
       No. of Female Employees: 544 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***