*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XF0575000
CHEMICAL NAME           : 1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane,
                          7,16-bis(2,3,3-trimethyl-1-diaziridinyl) methyl-,
                          (1-alpha(1R*,2S*),2-beta)-(+-)-
CAS REGISTRY NUMBER     : 106036-97-9
BEILSTEIN REFERENCE NO. : 5626485
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H46-N6-O4
MOLECULAR WEIGHT        : 458.74
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,10-Bis-(2,3,3-trimethyldiaziridino-1-methyl)-1,10-diaza-18-crown-6
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - irritability
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 20,385,1986
 
                            *** END OF RECORD ***