*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XF7470100
CHEMICAL NAME           : 1H-Tetrazole, 1-(m-aminophenyl)-5-isobutyl-,
                          hydrochloride
LAST UPDATED            : 198605
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H15-N5.Cl-H
MOLECULAR WEIGHT        : 253.77
WISWESSER LINE NOTATION : T5NNNNJ AR CZ& E1Y1&1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(m-Aminophenyl)-5-isobutyl-1H-tetrazole hydrochloride
   * TT-078
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 92,330,1948
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 92,330,1948
 
                            *** END OF RECORD ***