*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CC5075000
CHEMICAL NAME           : Antimony(V) chloride
CAS REGISTRY NUMBER     : 7647-18-9
LAST UPDATED            : 199712
DATA ITEMS CITED        : 37
MOLECULAR FORMULA       : Cl5-Sb
MOLECULAR WEIGHT        : 299.00
WISWESSER LINE NOTATION :  SB  G5
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Antimoine (pentachlorure d')
   * Antimonio (pentacloruro di)
   * Antimonpentachlorid
   * Antimony pentachloride
   * Antimoonpentachloride
   * Antimony perchloride
   * Pentachloroantimony
   * Pentachlorure d'antimoine
   * Perchlorure d'antimoine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1115 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Liver - hepatitis (hepatocellular necrosis), zonal
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   29(12),16,1964
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 720 mg/m3/2H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,22,1982
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 620 mg/m3
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 13(10),25,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Gastrointestinal - peritonitis
   Gastrointestinal - necrotic changes
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   29(12),16,1964
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 65 ug/disc
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 264,163,1991
 
TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 30 uL/disc
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 77,109,1980

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.5 mg(Sb)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.5 mg(Sb)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,15,1971

   OSHA PEL (Gen Indu):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-AUSTRIA:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-FINLAND:.TWA  (0.5 mg(Sb)/m3) JAN 1993
   
   OEL-FRANCE:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-GERMANY:TWA 0.5 mg(Sb)/m3 (total dust) JAN 1993
   
   OEL-HUNGARY:STEL 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-POLAND:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-RUSSIA:STEL 0.3 mg/m3 JAN 1993
   
   OEL-RUSSIA:TWA 0.2 mg(Sb)/m3;STEL 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO ANTIMONY-air:10H TWA 0.5 mg(Sb)/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4259
       No. of Facilities: 14 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 1452 (estimated)
       No. of Female Employees: 230 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: B subtilis rec assay
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***