*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CC9450000
CHEMICAL NAME           : Antimony trisulfide
CAS REGISTRY NUMBER     : 1345-04-6
LAST UPDATED            : 199712
DATA ITEMS CITED        : 38
MOLECULAR FORMULA       : S3-Sb2
MOLECULAR WEIGHT        : 339.68
WISWESSER LINE NOTATION :  SB2 S3
COMPOUND DESCRIPTOR     : Tumorigen
                          Human
SYNONYMS/TRADE NAMES :
   * Antimonous sulfide
   * Antimony Orange
   * Antimony sesquisulfide
   * Antimony sulfide (Sb2S3)
   * Antimony trisulfide colloid
   * Antimony vermilion
   * Black antimony
   * C.I. 77060
   * C.I. Pigment Red 107
   * Crimson antimony
   * Diantimony trisulfide
   * Lymphoscan
   * Needle antimony
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 580 ug/m3/35W
TOXIC EFFECTS :
   Cardiac - EKG changes not diagnostic of specified effects
   Vascular - BP elevation not characterized in autonomic section
   Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
   IMSUAI Industrial Medicine and Surgery.  (Northbrook, IL)  V.18-42, 1949-73.
    For publisher information, see IOHSA5.  Volume(issue)/page/year:
   23,521,1954
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1390 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   INMEAF Industrial Medicine.  (Chicago, IL)  V.1-18, 1932-49.  For publisher
   information, see IOHSA5.  Volume(issue)/page/year: 10,15,1941
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 209 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,23,1982
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : >139 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 8(7),25,1964

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.5 mg(Sb)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 47,291,1989

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 47,291,1989

   IARC Cancer Review:Group 3
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 47,291,1989

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.5 mg(Sb)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,15,1971

   OSHA PEL (Gen Indu):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.5 mg(Sb)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-AUSTRIA:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-FINLAND:.TWA  (0.5 mg(Sb)/m3) JAN 1993
   
   OEL-FRANCE:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-GERMANY:TWA 0.5 mg(Sb)/m3 (total dust) JAN 1993
   
   OEL-HUNGARY:STEL 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-POLAND:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-RUSSIA:STEL 1 mg/m3 JAN 1993
   
   OEL-RUSSIA:TWA 0.2 mg(Sb)/m3;STEL 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:STEL 0.5 ppm JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.5 mg(Sb)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO ANTIMONY-air:10H TWA 0.5 mg(Sb)/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M4884
       No. of Facilities: 786 (estimated)
       No. of Industries: 34
       No. of Occupations: 27
       No. of Employees: 26669 (estimated)
       No. of Female Employees: 1082 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   47,26992,82

 
                            *** END OF RECORD ***