*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CD4071900
CHEMICAL NAME           : Antithrombin III
CAS REGISTRY NUMBER     : 9000-94-6
OTHER CAS REGISTRY NOS. : 52014-67-2
                          9041-91-2
                          90170-80-2
LAST UPDATED            : 199806
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * AT-III
   * BI 6013
   * Heparin cofactor
   * Heparin cofactor B
   * Kybernin
   * Org 10849
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2000 units/kg
SEX/DURATION            : female 17-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 23,2963,1995
 
                            *** END OF RECORD ***