*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CE6230000 CHEMICAL NAME : L-Arabinose, 2-amino-4-((2-amino-1-oxopropyl)amino)-2,4-dideoxy-, (R)- CAS REGISTRY NUMBER : 38819-28-2 LAST UPDATED : 199107 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C8-H17-N3-O4 MOLECULAR WEIGHT : 219.28 WISWESSER LINE NOTATION : T5OTJ BMVYZ1 B1Q CQ DZ COMPOUND DESCRIPTOR : Drug Mutagen Natural Product SYNONYMS/TRADE NAMES : * 4-N-D-Alanyl-2,4-diamino-2,4-dideoxy-L-arabinose * Prumycin *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 70 mg/kg TOXIC EFFECTS : Skin and Appendages - hair Tumorigenic - active as anti-cancer agent REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 32,347,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 155 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,226,1980 ** MUTATION DATA ** TYPE OF TEST : DNA inhibition TEST SYSTEM : Human HeLa cell DOSE/DURATION : 10 mg/L REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,226,1980 *** END OF RECORD ***