*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CE8863000
CHEMICAL NAME           : Arbutin
CAS REGISTRY NUMBER     : 497-76-7
BEILSTEIN REFERENCE NO. : 0089673
REFERENCE               : 5-17-07-00110 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H16-O7
MOLECULAR WEIGHT        : 272.28
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * beta-Arbutin
   * beta-D-Glucopyranoside, 4-hydroxyphenyl-
   * Hydroquinone-beta-D-glucopyranoside
   * 4-Hydroxyphenyl-beta-D-glucopyranoside
   * Ursin
   * Uvasol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 13600 mg/kg
SEX/DURATION            : female 14 day(s) pre-mating
                          female 20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
   Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1- 1970- 
   Volume(issue)/page/year: 19,282,1988

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X1290
       No. of Facilities: 68 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 995 (estimated)
       No. of Female Employees: 745 (estimated)

 
                            *** END OF RECORD ***