*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CF9499000
CHEMICAL NAME           : Arsanilic acid, N-glycoloyl-, monosodium salt
CAS REGISTRY NUMBER     : 140-45-4
LAST UPDATED            : 198912
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C8-H8-As-N-O5.Na
MOLECULAR WEIGHT        : 296.08
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Allegan
   * Arsonic acid, (4-((hydroxyacetyl)amino)phenyl)-, monosodium salt
   * Quarcyl
   * Sodium N-glycolylarsanilate
   * Sodium p-N-glycolylarsanilate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 gm/kg
TOXIC EFFECTS :
   Behavioral - tremor
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,14,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5400 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,14,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 1060 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   4,14,1962
 
                            *** END OF RECORD ***