*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : CI9098500 CHEMICAL NAME : Aspartic acid, L- CAS REGISTRY NUMBER : 56-84-8 BEILSTEIN REFERENCE NO. : 1723530 REFERENCE : 4-04-00-02998 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C4-H7-N-O4 MOLECULAR WEIGHT : 133.12 COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * (S)-Aminobutanedioic acid * L-Aminosuccinic acid * Asparagic acid * L-Asparagic acid * Asparaginic acid * L-Asparaginic acid * Aspartic acid * (L)-Aspartic acid * L-(+)-Aspartic acid * (S)-Aspartic acid *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 6 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,569,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 25079 mg/kg/7D-C TOXIC EFFECTS : Liver - other changes Biochemical - Metabolism (Intermediary) - lipids including transport REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,738,1982 ** MUTATION DATA ** TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 10 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81861 No. of Facilities: 803 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 5939 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81861 No. of Facilities: 634 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 9033 (estimated) No. of Female Employees: 6545 (estimated) *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: Sperm morphology-human EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***