*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CI9463000
CHEMICAL NAME           : Aspartic acid, L-, compd. with L-ornithine (1:1)
CAS REGISTRY NUMBER     : 3230-94-2
LAST UPDATED            : 199701
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C5-H12-N2-O2.C4-H7-N-O4
MOLECULAR WEIGHT        : 265.31
SYNONYMS/TRADE NAMES :
   * L-Aspartic acid compd. with L-ornithine (1:1)
   * Hepamerz
   * Ormeta
   * Ornithine aspartate
   * L-Ornithine L-aspartate
   * Orparan
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IPAE "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical,
   Medical and Dental Supply Exporters' Assoc.,  1968 Volume(issue)/page/year:
   -,91,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,164,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,164,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IPAE "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical,
   Medical and Dental Supply Exporters' Assoc.,  1968 Volume(issue)/page/year:
   -,91,1968

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***