*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CJ0120000
CHEMICAL NAME           : Aspidospermidine-3-carboxylic acid,
                          4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-
                          methyl-, methyl ester,
                          (2-beta,3-beta,4-beta,5-alpha,12-beta,19-alpha)-
CAS REGISTRY NUMBER     : 2182-14-1
LAST UPDATED            : 198009
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H32-N2-O6
MOLECULAR WEIGHT        : 456.59
WISWESSER LINE NOTATION : T C6 B5665 2AB S BX IN QN NU JH&&TTTJ FO1 I1 KVO1 KQ
                          LOV1 M2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Vindolin
   * Vindoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
REFERENCE :
   33GVAL "Catharanthus Alkaloids," Taylor, W.I., and N.R. Farnsworth, eds.,
   New York, Marcel Dekker, 1975  Volume(issue)/page/year: -,73,1975
 
                            *** END OF RECORD ***