*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CJ9930000
CHEMICAL NAME : Atriopeptin-21(rat),21a-L-phenylalanine-21b-L-arginin
e-21c-L-tyrosine-, hydrochloride
CAS REGISTRY NUMBER : 130835-58-4
LAST UPDATED : 199403
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C107-H165-N35-O34-S2.Cl-H
MOLECULAR WEIGHT : 2586.65
SYNONYMS/TRADE NAMES :
* Apiii hydrochloride
* Atriopeptin-24 (rat) hydrochloride
* Atriopeptin III (rat) hydrochloride
* Rat ANP-(103-126) hydrochloride
* Rat atriopeptin III hydrochloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-
1990- Volume(issue)/page/year: 1,717,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-
1990- Volume(issue)/page/year: 1,717,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Primate - monkey
DOSE/DURATION : >1 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-
1990- Volume(issue)/page/year: 1,717,1992
*** END OF RECORD ***