*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CL1201000
CHEMICAL NAME           : Avermectin A(sub 1a), 5-O-demethyl-, (13R)-, hydrate
CAS REGISTRY NUMBER     : 135681-09-3
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C48-H72-O14.H2-O
MOLECULAR WEIGHT        : 891.22
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 13-epi-Avm B(sub 1) hydrate
   * (13R)-5-O-Demethylavermectin A(sub 1a) hydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 35,3873,1992
 
                            *** END OF RECORD ***