*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH3942000
CHEMICAL NAME           : Theophylline, 8-((2-aminoethyl)amino)-
CAS REGISTRY NUMBER     : 14251-32-2
BEILSTEIN REFERENCE NO. : 1005639
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H14-N6-O2
MOLECULAR WEIGHT        : 238.29
WISWESSER LINE NOTATION : T56 BN DN FVNVNJ CM2Z G1 I1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-((2-Aminoethyl)amino)theophylline
   * 1H-Purine-2,6-dione, 8-((2-aminoethyl)amino)-3,7-dihydro-1,3-dimethyl-
   * Theophylline ethylene-diamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 22,265,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 22,265,1964
 
                            *** END OF RECORD ***