*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XF8882000 CHEMICAL NAME : Tetrodotoxin, 4,9-anhydro- CAS REGISTRY NUMBER : 13072-89-4 LAST UPDATED : 199206 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H15-N3-O7 MOLECULAR WEIGHT : 301.29 SYNONYMS/TRADE NAMES : * Anhydroepitetrodotoxin * Anhydrotetrodotoxin * 4,9-Anhydrotetrodotoxin * (4-beta,9-beta)-4,9-Dideoxy-4,9-epoxytetrodotoxin * Tetrodotoxin, 4,9-dideoxy-4,9-epoxy-, (4-beta,9-beta)- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 16900 ug/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 17,267,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 986 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 3,58,1968 *** END OF RECORD ***