*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH5074000
CHEMICAL NAME           : Theophylline, 8-chloro-, compd. with
                          10-(2-(dimethylamino)propyl)phenothiazine (1:1)
CAS REGISTRY NUMBER     : 17693-51-5
LAST UPDATED            : 199110
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H20-N2-S.C7-H7-Cl-N4-O2
MOLECULAR WEIGHT        : 499.08
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Avomine
   * Promethazine chlorotheophyllinate
   * Promethazine theoclate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,1052,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,1052,1990
 
                            *** END OF RECORD ***