*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH5095500
CHEMICAL NAME           : Theophylline, 7-(2-(diethylamino)ethyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 17140-68-0
OTHER CAS REGISTRY NOS. : 60508-93-2
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H21-N5-O2.Cl-H
MOLECULAR WEIGHT        : 315.85
WISWESSER LINE NOTATION : T56 BN DN FNVNVJ B2N2&2 F1 H1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Chlorhydrate de diethylaminoethyltheophylline
   * 7-(beta-Diaethylamino-aethyl)-theophyllin-hydrochlorid
   * 7-(2-(N,N-Diethylamino)ethyl)theophylline hydrochloride
   * Etamiphylline hydrochloride
   * Etamiphyllin hydrochloride
   * 1H-Purine-2,6-dione, 7-(2-(diethylamino)ethyl)-3,7-dihydro-1,3-dimethyl-, 
    hydrochloride
   * Solufilina
   * ST
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 182 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle contraction or spasticity
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,190,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 127 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 103,146,1955
 
                            *** END OF RECORD ***