*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : XH5161000
CHEMICAL NAME : Theophylline-8-ethanol,
alpha-((diisobutylamino)methyl)-, benzoate (ester)
CAS REGISTRY NUMBER : 102367-57-7
LAST UPDATED : 199609
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C25-H35-N5-O4
MOLECULAR WEIGHT : 469.65
WISWESSER LINE NOTATION : T56 BM DN FNVNVJ C1YOVR&1N1Y1&1&1Y1&1 F1 H1
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Diisobutylaminobenzoyloxypropyl theophylline
* 7-(3-Diisobutylamino-2-benzoyloxypropyl)theophylline
* alpha-((Diisobutylamino)methyl)theophylline-8-ethanol benzoate (ester)
* Vestphyllin
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IPAE "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical,
Medical and Dental Supply Exporters' Assoc., 1968 Volume(issue)/page/year:
-,101,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1835 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,306,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 273 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,306,1982
*** END OF RECORD ***