*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH5603000
CHEMICAL NAME           : Theophylline, 8-ethyl-7-hydroxy-
CAS REGISTRY NUMBER     : 4227-23-0
BEILSTEIN REFERENCE NO. : 0618907
REFERENCE               : 5-26-14-00181 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C9-H12-N4-O3
MOLECULAR WEIGHT        : 224.25
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-Ethyl-7-hydroxytheophylline
   * GD 073
   * 7-Hydroxy-8-aethyltheophyllin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 290 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   21,501,1968
 
                            *** END OF RECORD ***