*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH5775000
CHEMICAL NAME           : Theophylline, 7-hydroxy-
CAS REGISTRY NUMBER     : 1012-82-4
BEILSTEIN REFERENCE NO. : 0616325
REFERENCE               : 5-26-14-00133 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C7-H8-N4-O3
MOLECULAR WEIGHT        : 196.19
WISWESSER LINE NOTATION : T56 BN DN FNVNVJ BQ F1 H1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 7-Hydroxytheophyllin
   * 7-Hydroxytheophylline
   * 1H-Purine-2,6-dione, 3,7-dihydro-7-hydroxy-1,3-dimethyl-
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg/24W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 21,356,1971
 
                            *** END OF RECORD ***