*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XH6487400 CHEMICAL NAME : Theophylline, 8-(2-piperidyl)-, hydrochloride CAS REGISTRY NUMBER : 96434-25-2 LAST UPDATED : 199112 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C12-H17-N5-O2.xCl-H MOLECULAR WEIGHT : 518.56 WISWESSER LINE NOTATION : T56 BN DN FVNVNJ C- BT6NTJ G1 I1 &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Chlorhydrate de piperidyl-2' theophylline * 8-(2-Piperidyl)theophylline hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1138 mg/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - sleep Behavioral - convulsions or effect on seizure threshold REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 22,265,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 856 mg/kg TOXIC EFFECTS : Behavioral - excitement Behavioral - changes in motor activity (specific assay) REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 22,265,1964 *** END OF RECORD ***